Moxonidine Hydrochloride Catalog No.:M8975-10 Per2 and Nr1d1 in both

Per2 and Nr1d1 in both liver and pancreas by 4

also known as N-Methylisoindigotin and Dian III

is a naturally occurring indole alkaloid present in several plant species

23(7):1222-33

UNII-1999398A3P

Moxonidine Hydrochloride Catalog No.:M8975-10 Per2 and Nr1d1 in bothMoxonidine(BDF5895) is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent. Target: I1 RMoxonidine is a centrally acting antihypertensive agent. Mixed Nischarin (I1 imidazoline receptor) and 2 AR (adrenergic) agonist; displays 40 fold higher affinity for I1 receptors versus 2 adrenoceptors. Moxonidine reduced stimulated NE overflow (log EC50: 6. 15 + 0. 14). AGN192403, a selective ligand at I1 R, had no influence